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Researchers from Beaumont Health System, Michigan, have been studying the mechanism of stem cell response to injury that may have clinical implications for the treatment of osteoarthritis. Working with rodent models, they report that injury to the anterior cruciate ligament (ACL) provokes...
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Scientists at the Scripps Research Institute (TSRI) have reported success in their latest trial on nonhuman primates of a vaccine that blocks the “high” from heroin, the first such opioid blocking substance to pass this stage of preclinical testing. Lead author Kim Janda, PhD, stated, “This...
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With more than 54 million Americans presently impacted by arthritis, sales of the essential oil Copaifera reticulate or copaiba are on the rise. Copaiba is a stimulant oleoresin with medicinal usage dating back to the 16th century. It is derived from the trunk of several South American leguminous...
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A research team led by Eóin McNamee, PhD, at University of Colorado-Anschutz Medical Campus, has identified a microRNA produced by white blood cells that can modulate the inflammasome responsible for inflammatory bowel diseases (IBD), including Crohn’s disease and ulcerative colitis. The study in...
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Researchers from Texas A&M University are seeking to develop new drugs that alter the function of nicotinic acetylcholine receptors in the brain which, if successful, may result in new treatment options for conditions that include nicotine addiction, Alzheimer’s, and other memory disorders, as well...
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Findings from a study conducted by a team from Rush University Medical Center, Chicago may help to explain the higher incidence of complications from total hip and knee replacement surgery in women as compared to men. The study implicates hypersensitivity to metals as a probable culprit. The team...
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A study led by researchers from Georgia State University, in collaboration with colleagues from Emory University and University of Michigan, reports that the regulation of inflammatory bowel disease (IBD) by immune cells can be affected by a specific cytokine or small protein. Cytokine IL-36γ was...
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A research team from the University of Chicago and the University of Pittsburgh School of Medicine reports that reovirus, a common and usually harmless virus, can provoke an immune system response to gluten that causes celiac disease. The discovery, and the related suggestion that viruses could be...
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A new study conducted at Houston Methodist Hospital reports that patients with prolonged inflammatory bowel disease (IBD) are at greater risk for developing nonalcoholic fatty liver disease (NAFLD). Patients who develop the 2 conditions are also likely to be older, according to the findings. The...
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An article published online earlier this week in the Journal of Neurosurgery suggests that candidates for lumbar spinal fusion surgery may be well advised to discontinue lumbar epidural steroid injections (LESIs) for up to 3 months before undergoing the procedure. Drawing on conclusions from their...