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A first of its kind randomized, controlled, double-blinded clinical trial has confirmed the effectiveness of botulinum toxin A in combination with physical therapy in treating chronic sciatica and buttock pain arising from piriformis syndrome. The study was led by Loren Fishman, MD, assistant...

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Researchers at Hospital for Special Surgery (HSS) report that the incidence of myocardial ischemia in patients with risk factors for cardiac events is high following major orthopedic surgery, although the frequency of serious cardiac complications remains low. The study authors recommend a blood...

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Results of new research presented last week at the annual meeting of the American Orthopaedic Society for Sports Medicine in Toronto confirm the efficacy of 3 commonly used surgical techniques used to treat tears of the anterior cruciate ligament (ACL). Author and presenter Nicholas Mohtadi, MD, MSc...

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An international clinical trial published in the Lancet focuses on preserving muscle function in Duchenne muscular dystrophy, a rare but fatal genetic disorder. Caused by an absence of dystrophin, a protein that helps keep muscle cells intact, the disorder is characterized by progressive muscle...

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Researchers from University of Chicago School of Medicine report evidence from a study in mice that antibiotics administered in late pregnancy and early nursing can increase the risk for development of inflammatory bowel diseases (IBD) in offspring. Antibiotics also caused lasting changes in the gut...

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The effectiveness of cognitive behavioral therapy (CBT) as an intervention for chronic pain may be enhanced through the use of acceptance and commitment therapy (ACT), according to new research conducted at Kings College, London. ACT includes a therapeutic process that engages the contextual self...

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Identified: 3 inflammatory biomarkers that may be useful in assessing the likelihood of secondary effects from traumatic brain injury, according to new research from the University of Birmingham in the UK. Lisa Hill, PhD, with the Institute of Inflammation and Ageing at the University of Birmingham...

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A new study conducted by researchers from University of New South Wales, Sydney, Australia, suggests that the measurement of substance P in tear samples may provide a reliable marker for diabetes related neuropathy. Substance P is a neuropeptide involved in wound healing as well as contributing to...

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Researchers from Case Western Reserve University School of Medicine report that high levels of the fungus Candida tropicalis may trigger inflammation and intensify painful colitis in sufferers of Crohn’s disease. In their study of mouse models, the team induced colitis symptoms in mice by adding...

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New research conducted by a team in Australia reports that immune system exhaustion is associated with diarrhea-predominant irritable bowel syndrome (IBS-D), a specific type of the disease. The study followed patients with various types of IBS, comparing blood work over a period of 1 year that...

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