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A primate mostly found in Asia may hold the key to better treatment of rheumatoid arthritis (RA), according to findings from a new study conducted by researchers at the Keck School of Medicine of USC. The monkeys carry a peptide, θ-defensin 1 (RTD-1), that the team found effective in halting and...
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Building on 2 decades of past research, scientists from the Florida campus to The Scripps Research Institute (TSRI) have announced noteworthy progress in the search for a new opioid that delivers the analgesic equivalent of morphine without the major adverse effect of respiratory depression...
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New work on mouse models suggests that a fresh approach to re-engineering the gut microbiome may yield an effective treatment for Crohn’s disease. Researchers from the Perelman School of Medicine at the University of Pennsylvania have isolated a single bacterial enzyme, known as urease, which is...
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New research using rat models has found that ibuprofen reduced neuroinflammation and behavioral signs of alcohol exposure associated with fetal alcohol spectrum disorders (FASD). As reported by Ohio State University, the study is the first to connect alcohol-induced inflammation in the hippocampus...
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Researchers from Johns Hopkins University School of Medicine have discovered a previously unknown immune mechanism that can provoke inflammation of the skin from conditions including atopic dermatitis (eczema). This mechanism involves activation of a protein by commonly present Staphylococcus aureus...
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Researchers from Mt. Sinai Health System report their conclusion that patients with Crohn’s disease whose condition was monitored by both clinical symptoms and inflammation biomarkers achieved superior treatment outcomes in comparison to patients whose treatment was guided by symptoms alone. In...
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Findings from new research conducted at Mayo Clinic may help to better define the conditions warranting invasive diagnostic testing of patients suffering from cerebrospinal fluid (CSF) hypovolemia. CSF hypovolemia is a condition in which a spontaneous leak from the spine depletes cerebrospinal fluid...
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Warfarin, commonly prescribed to prevent blood clots in patients undergoing joint replacement surgery, is associated with a range of adverse effects that include major bleeding and requires careful, individualized dosing to achieve the best possible treatment outcomes. A new study finds that...
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Researchers from The Scripps Research Institute (TSRI) Florida campus have recently achieved new insight into a prime target for osteoporosis treatment, an advance that may enable the development of more effective therapies for the condition. The target is a receptor that regulates calcium levels to...
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A research team from SUNY Upstate Medical University in collaboration with Erasmus Medical Center, the Netherlands has connected a deficiency in a protein from the SHIP1 gene with the presence of inflammatory bowel disease (IBD). The finding could be of value in guiding the identification and...