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A side effect of many anticancer drugs is chemotherapy induced peripheral neuropathy (CIPN), the pain from which can substantially diminish cancer survivors’ quality of life and even provoke cessation of their chemotherapy. Daniela Salvemini, PhD, Professor of Pharmacology and Physiology at the...
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Findings from a small study of patients diagnosed with central poststroke pain (CPSP) are being characterized as a significant advance in our understanding of the pain mechanisms underlying the condition. In the study, conducted by researchers from the Washington University Pain Center and...
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Researchers from the University of Michigan School of Medicine report that environmental factors such as cigarette smoke and other pollutants may heighten the risk for developing rheumatoid arthritis (RA) in genetically susceptible individuals and may be responsible for more severe damage when RA...
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Working with animal models, researchers from Saint Louis University report success in attenuating the debilitating pain that is a common side effect of chemotherapy for colorectal cancer. Chemotherapy induced neuropathic pain (CINP) manifests as numbness or tingling in the hands and feet, or as...
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An innovative approach to patient evaluation may offer a significant improvement in the treatment of rheumatoid arthritis, according to researchers from Northwestern University Feinberg School of Medicine. The team believes that genetic profiling of joint tissue can enable better matching of...
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Bioengineers at the Center for Multimodal Evaluation of Engineered Cartilage at Case Western University report a significant advance in the science of tissue engineering that produces stronger and more durable material for articular cartilage repair. Senior author Harihara Baskaran, PhD, professor...
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New research on mouse models from Case Western Reserve University School of Medicine warns that sucralose, the artificial sweetener contained in the brand Splenda can exacerbate the gut inflammation that accompanies Crohn’s disease. Researchers studied mice from a genetic line that is affected by a...
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Researchers from Wake Forest Baptist Medical Center report that a new technology improves the measurement of a known biomarker for osteoarthritis and other inflammatory diseases. In a preclinical study, the team engaged a solid-state nanopore sensor to assess the presence of hyaluronic acid (HA), a...
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Findings from new research conducted at the University of Calgary suggest an approach to treating pediatric inflammatory bowel disease (IBD) that is novel, if somewhat difficult to read about: tapeworms. The work builds on previous experimental findings that adult animals previously infected with...
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A study in Sweden reports that patients who elect to undergo total hip arthroplasty (THA) not only report improved quality of life, but also live longer, compared to other people of comparable age and sex. Study author Peter Cnuddle, MD, with the Swedish Hip Arthroplasty Register, Gothenburg...