| Article
Researchers from Dana-Farber Cancer Institute report the discovery of the mechanism by which some chemotherapy drugs cause peripheral neuropathy (CIPN). The knowledge may be useful in the development of new preventative measures that can protect patients undergoing chemotherapy from the risk of...
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Chronic pain may centralize in the brain and spinal cord, leading to constant neuropathic pain. Dr. Tennant discusses the mechanism of development, available diagnostic tools, and s why under recognition of neuroinflammation is one of our major problems in pain management.
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A professor of physical medicine and rehabilitation discusses the treatment of neuropathic pain and what the primary care clinician should know and do. Addressing the whole patient via an interdisciplinary team is the key to better outcomes. Specific points on Fibromyalgia, CRPS, and Ketamine as...
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Substantial evidence suggests that lifestyle factors can be of significant benefit in the management of symptoms, including pain, resulting from multiple sclerosis (MS). A recent study appearing in the journal Frontiers of Neurology adds further weight to this consensus, finding that regular...
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Results from a recent phase 2 clinical trial have come up short in the search for a compound that ameliorates pain through improvements in sleep. The study investigated the efficacy of filorexant, an orexin receptor antagonist in providing relief from painful diabetic neuropathy (PDN). In rodent...
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An article published earlier this week in Pharmacy Times sheds additional light on the extent of the problem of undertreated diabetes, especially in rural areas. The author, Jeannette Wick, RPh, MBA, FASCP, cites a 17% higher incidence of diabetes in rural areas compared to urban locations, with...
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New research conducted at West Virginia University School of Medicine in Morgantown concludes that dorsal root ganglion (DRG) stimulation is more effective than spinal cord stimulation (SCS) at providing relief for patients with neuropathic pain affecting the lower extremities. Refractory...
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The Agency for Healthcare Research and Quality (AHRQ), the lead federal agency charged with improving patient safety and healthcare quality, has published new findings on the effectiveness of some antidepressants, antiseizure drugs, and other medications in treating diabetic peripheral neuropathy...
| Article
A pilot study conducted by researchers at the University of Texas MD Anderson Cancer Center concludes that neurofeedback training may be an effective treatment modality for the management of chemotherapy-induced peripheral neuropathy (CIPN). CIPN causes symptoms that include pain, loss of feeling...
| Podcast
Chronic pain may centralize in the spinal cord and brain leaving the patient with constant, neuropathic pain. The mechanism of this development is microglial activation and neuroinflammation. Successful treatment usually requires a special pharmacologic regimen that includes analgesics, neuropathic...