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Why/how do NSAIDs do what they do? They are used for their anti-inflammatory effects, but is that all? Research published in Immunity examined an NSAID subset that activates nuclear factor erythroid 2-related factor 2 (NRF2). NRF2 controls some genes that participate in processes including...
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The Journal of Medical Internet Research has published an article on the use of smartphones to help combat chronic pain. 209 patients with chronic musculoskeletal pain were randomized to an intervention group, with web-based psychosocial therapy through a smartphone, while the control group could...
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A veteran’s self-reported level of trauma/pain is important but doesn’t always give clinicians an objective measurement. A new study published in Frontiers in Pain Research identified connection strength via functional magnetic resonance imaging of army veterans’ brain regions. By scanning 57...
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Finger joint osteoarthritis is experienced by half of men over age 60 and half of women over age 50, causing pain and decreased strength and range of motion. An article in the journal of Plastic and Reconstructive Surgery reports an alternative to conventional surgery for patients with arthritic...
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Although up to 60% of patients with opioid use disorder (OUD) also have chronic pain, the conditions have been mostly studied separately. A $4 million grant from the National Institutes of Health’s Helping End Addiction Long-term Initiative to the Wake Forest University School of Medicine hopes to...
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The journal of Children reports on new guidelines for a pervasive health concern. With a monthly prevalence of 20% in young kids, potentially leading to a lifetime prevalence of 40%, back pain is serious. The guideline, developed by 14 professional societies in Germany, is based on a literature...
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Unsedated procedures involving patients who have acute or chronic illness can be painful and cause nervousness, anxiety, distress, and catastrophizing. Virtual reality (VR) has been shown to positively distract, and therefore lessen the stress involved. The Journal of Medical Internet Research repor...
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A study in the ACR Open Rheumatology journal determined that people with rheumatoid arthritis (RA) are undermedicated—STILL, even though guidelines have called for early and aggressive treatment. Researchers looked into over 7,800,000 ambulatory visits by older adults over 12 years. Rheumatologists...
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Pediatric pain assessment and management are frequently underestimated and undertreated. Therefore, those practitioners working in the emergency sector should be ready with strategies. An article in the Journal of the American College of Emergency Physicians Open provides suggestions for pain and...
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What is the association between chronic low back pain (CLBP) and regional brain atrophy? A Japanese study asked that question and answers are published in the journal Pain. Basically, the part of the brain that processes pain may have atrophied. Over 1100 participants 65 years or older were put into...