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Why/how do NSAIDs do what they do? They are used for their anti-inflammatory effects, but is that all? Research published in Immunity examined an NSAID subset that activates nuclear factor erythroid 2-related factor 2 (NRF2). NRF2 controls some genes that participate in processes including...
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Newswise — About 29 million Americans use over-the-counter nonsteroidal anti-inflammatory drugs (NSAIDs) to treat pain. Every year in the United States, NSAID use is attributed to approximately 100,000 hospitalizations and 17,000 deaths. In addition, the U.S. Food and Drug Administration recently...