| Article
In an article in the Cell journal, scientists from China and the University of North Carolina School of Medicine have researched the structural framework of opioid receptors in an effort to build better pain management and limit side effects. “This collaboration revealed conserved, or shared...
| Article
The journal of Arthritis & Rheumatology reports on a pain management procedure for knee osteoarthritis. In a randomized, placebo controlled 12 week trial, 59 patients received either injections of saline (placebo) or 3 injections of celestone chronodose and bupivacaine to the genicular nerves...
| Article
Chronic migraine is disabling, complex, and an expensive global burden; it has also been studied far less than episodic migraine. A review in BMJ focused on treatments, including calcitonin gene related peptide antagonists and neuromodulatory devices. Via keywords searches, including “chronic...
| Article
The 2016 Centers for Disease Control and Prevention Guideline for Prescribing Opioids for Chronic Pain was controversial; did it change minds? Apparently it did get practitioners to think “nonopioids” more often. An article published in JAMA Network Open presented information based on cohort study...
| Article
The Lancet Public Health journal published findings from a study of opioid analgesic consumption in 66 countries and found great disparity. Consumption was measured in milligram morphine equivalent per 1000 inhabitants per day (MME per 1000/day), from 2015 to 2019. Of much concern, “Opioid use in...
| Article
In a narrative review published in Cureus, researchers examined acute pain, which is normal postsurgery, and its potential transition to chronic pain. Postsurgery rates of persistent/subacute pain (lasting over a month) range from 10% to 50%; chronic pain (lasting more than 3 months) is seen in 2%...
| Article
One patient, multiple doctors, multiple medications. A study published in JAMA Network Open looked at benzodiazepines and opioid prescribing and, even when adjusted for patient characteristics and prescription dosing, a 20% higher risk of overdosing was seen. Data from over 525,000 patients was...