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According to the CDC, OA affects over 32.5 million US adults. Discovery of a new molecular signaling pathway, therefore, could be important. The research, published in Frontiers in Neuroscience, presents “the first evidence of a potential functional role of artemin/GFRα3 in chronic OA-pain in mice...
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Do you have a patient with degenerative disc disease? The statistics say that YES you probably do: 40% of people over age 40 and 80% of people over age 80 experience degenerative disc disease. But does that make them good candidates for a cervical implant? Surgeons rely on imaging studies to help...
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Postsurgery, who needs which kind of pain management medication? A study published in The Annals of Thoracic Surgery looks at opioid-naïve patients who underwent coronary artery bypass grafting and/or valve surgery. Of more than 1900 patients, 28% were discharged without a prescription for opioids...
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JAMA Neurology reports findings gathered from over 2600 migraine sufferers, aged 18 to 65, from 4 randomized clinical trials. Researchers sought to determine whether erenumab would improve migraine frequency and lessen migraine medication need in those with and without aura. The study notes, “One or...
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Kids need shots and shots can hurt. What can practitioners do to help their littlest patients? Specialists from the Children’s Hospital Los Angeles offer tips for both practitioners and parents of kids who will be facing needles. While being candid is key, there is no reason to instill fear...
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The Journal of Orthopaedic Surgery and Research reports the potential benefits of combination therapy after posterior spinal fusion for idiopathic scoliosis in adolescents. While it is known that pain scores, postop opioid usage, and needed physical therapy are reduced through the use of gabapentin...
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What are the best treatments for painful diabetic neuropathy? The American Academy of Neuropathy, with an endorsement by the American Association of Neuromuscular & Electrodiagnostic Medicine, has updated its 2011 guidelines for oral and topical treatments. The recommendations, which may reduce as...
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After thoracic surgery, chronic neuropathic pain is common—3 months postsurgery, the rate of postthoracotomy pain syndrome (PTPS) is over half; at 6 months, 47%. Symptoms/complications include shooting/burning pain, shocking, and aching pain that can last years. A study published in the Journal of...
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The American Journal of Physiology-Cell Physiology has published an article on the long term complications of COVID-19, its impact on various organ systems, and potential management algorithms. In the United States, COVID has infected >49 million; approximately 26% experience long term complications...
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The journal of Anesthesiology featured a special article in which a new concept is presented: a prescription opioid ecosystem. The need for this ecosystem stems from the “opioid paradox” that, even though the past 10 years has seen a drop in opioid prescribing of about 38%, deaths from opioids have...