| Article
A study conducted by researchers from NorthShore University Health System, Evanston, Illinois, reports that patients who receive intraoperative methadone during spinal fusion surgery need lower quantities of opioids, both oral and intravenous, to manage their postoperative pain. Lead author Glenn...
| Article
Evidence-based medicine is how we connect research to clinical practice. It started in the 80s and 90s as of way of looking at how studies are done and how they could be applied to clinical care, and it’s gone through a number of changes over the years. Evidence-based medicine now is being applied...
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The nationwide opioid abuse epidemic has directed a lot of attention from the state and federal levels on the primary care provider. The CDC guidelines for the prescribing of opioids for acute pain can do a lot to help a provider to steel himself or herself in the event that there is inquiry into...
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Will recently released prescribing guidelines from the CDC advance the cause of rational opioid therapy? Will they lead to better pain practice and better patient outcomes? Dr. Argoff considers the good, the bad, and the ugly...
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Research conducted at University of North Carolina School of Medicine sheds new light on the cause of a frequently encountered side effect of opioid therapy, intense itching. UNC scientists report that the receptor protein MRGRPX2 may be activated to trigger an immune system response that results in...
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Much of the publicity today, as well as initiatives like the CDC guidelines, really focus on the outpatient problems with chronic pain patients. But there’s a growing concern with how we prescribe opioids for post-op pain control. There is a fair amount of literature that’s emerging about whether...
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A research team from the Icahn School of Medicine at Mount Saini reports new discoveries relating to the molecular causes of heroin addiction that, according to their additional work on rodent models, may point the way to new and promising therapeutic tools for opioid use disorder in humans. The...
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The challenge to prescribers seeking to manage their patients’ chronic pain while addressing the risk for opioid related adverse events has escalated with the increasing use of opioid therapy over the last 2 decades. A recent study by a team that included PAINWeek faculty member Beth Darnall, PhD...
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One approach to maintaining the balance between risks and benefits of opioid therapy for chronic pain has been the development of abuse deterrent formulations. A pain management PA provides an overview of abuse deterrent technologies, both existing and emerging. While developments are encouraging...
| Podcast
The field of pain management has undergone a circuitous adventure, much like a rabbit hole. As the economic, mental health, and medical consequences of prescribing opioid medications have mounted, the prevailing logic regarding the usefulness of prescribing opioids for chronic pain has shifted. The...