Addressing the Void in Pain Research

Last week, the National Institutes of Health announced a major new research commitment devoted to advancing the national response to the crisis of opioid abuse and addiction. The HEAL (Helping to End Addiction Long-term) Initiative will be a multiagency initiative to advance scientific research on a...

Surgeon General: Make Naloxone Widely Available

Last week, US Surgeon General Jerome Adams, MD, MPH, issued an advisory advocating for greater distribution and availability of naloxone as an element of the national response to opioid use disorder. The Surgeon General recommends that individuals at risk for opioid overdose, as well as their family...

Does the Opioid Threat Go Beyond Opioids?

In 2017, the state of Kentucky became the first to classify gabapentin as a Schedule 5 substance, following the finding that the drug was involved in up to 33% of overdose fatalities during the prior year. This means that prescriptions for gabapentin will be reported to the state’s PDMP going...

Overdose! Are Drug Users the Best First Responders?

Because they are likely to be at the scene of an overdose when it occurs, fellow drug users may be the most suitable targets for naloxone training, according to conclusions from a new study conducted at Johns Hopkins Bloomberg School of Public Health. In interviews with 450 drug users in the...

Are Better-Educated Boomers More Likely to Abuse Opioids?

A new study conducted by researchers from the University at Buffalo School of Nursing is one of the first to focus specifically on the risk factors for opioid misuse in older adults. This population is particularly sensitive to adverse effects from opioids, according to the researchers. Study author...

Chronic Opioid Therapy and Spinal Fusion

Findings from new research conducted at the Ohio State University Wexner Medical Center conclude that long-term opioid therapy is associated with an increased risk of complications following spinal surgery. Lead author Safdar Kahn, MD,  an orthopedic spine surgeon at Wexner Medical Center’s...

Managing Chronic Pain: Should You Start with Opioids or Nonopioids?

In a step to address the dearth of clinical research on opioid therapy for chronic pain, a new long-term study finds no advantages to opioid medications over nonopioids for the management of pain from hip or knee osteoarthritis or chronic back pain. Lead author Erin Krebs, MD, MPH, with the...

Reducing Medication Burden While Managing Chronic Pain

Per the department of Health and Human Services, opioid related overdose deaths have increased almost 400% over the last 18 years. This shift has yielded heightened scrutiny of prescribing practices, and opioids have subsequently fallen out of favor as a first-line treatment for chronic pain. In...

Can a Failed Osteoarthritis Drug Have Other Pain Management Uses?

Although human trials of a new compound developed by Eli Lily and Co. for the treatment of osteoarthritis failed to demonstrate efficacy, the drug may still have substantial utility in the pain management armamentarium. Findings from a study conducted by researchers from Indiana University suggest...

Abuse Deterrent Technologies to Minimize Opioid Abuse

Although opioids remain an important tool in aiding the management of pain in the United States, the balance between the potential benefits and harms must be considered. Some specific harms are manifested in the abuse of opioids for nonmedical purposes. The primary access to prescribable opioids for...