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One hundred million Americans experience chronic pain, contributing to an estimated 560 to 635 billion dollars annually in medical costs. This is a fast-growing problem; importantly, not all pain is the same. Pain is a complex and subjective experience that keeps us away from injury and harm. It is...
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The journal of Science reports findings from researchers accessing chemotypes from a virtual library of over 300 million molecules. The authors of the study “computationally docked each virtual molecule into the highly similar α2BAR binding site, prioritizing those that physically fit and that were...
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The journal of Anesthesiology published a report on the viability of pain management medication development. Using a database and over 1600 data points, researchers analyzed variables to note the probability of “success, duration, and survivorship of pain medication development programs between...
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Pain often brings about anxiety and depression, which in turn can worsen the pain. The Journal of Neuroscience has published a paper entitled GABAergic CaMKIIα+ Amygdala Output Attenuates Pain and Modulates Emotional-motivational Behaviour via Parabrachial Inhibition. In their Significance Statement...
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Pain is affected by fear and anxiety about pain. How does that relationship change over the span of a life? The abstract of an article in the Pain Medicine journal states that "Nociception and pain history differ depending on age, yet little empirical evidence exists on how fear of pain varies over...
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Objective: The present study assessed somatosensory changes related to trigeminal nerve damage using extensive evaluation tools and assessed the effect of such damage on the patients’ psychosocial status and quality of life compared with healthy participants.
Methods: In 37 patients with...
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Newswise — Tuberculosis is distinguished primarily by the persistent cough that serves to spread the disease. Stopping whatever triggers that cough could greatly reduce the transmission of the disease, which annually kills more than 1.3 million people worldwide.
Researchers from The...
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Newswise — Identifying the type of pain an adult with sickle cell disease (SCD) experiences may be useful in improving treatment, according to a new study by researchers at Yale Cancer Center (YCC) and Smilow Cancer Hospital. The findings are to be presented Saturday, December 7, 2019 at the 61st Am...