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Does childhood maltreatment contribute to higher rates of pain catastrophizing in those with immune-mediated inflammatory disease (IMID)? Researchers asking that question published their findings in the Journal of Psychosomatic Research. Over 570 people with multiple sclerosis, irritable bowel...
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For those patients whose ulcerative colitis is unmanageable, a surgical procedure called a restorative proctocolectomy with ileal pouch-anal anastomosis may be performed. The J-pouch procedure involves a pouch being constructed from healthy tissue from the small intestine, which replaces the section...
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The American College of Gastroenterology has published its first-ever guideline for the management of irritable bowel syndrome. Guideline coauthor Brian E. Lacy, MD, PhD, FACG, commented, "We identified 25 clinically important questions that clinicians frequently ask and then used GRADE (Grading of...
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Colitis is a major health problem in the United States. A Science Translational Medicine article states that mice fed a diet high in sugar had aggravated colitis. While high-fat diets may trigger inflammatory bowel disease, the role of sugar has been controversial, according to Hasan Zaki, PhD, lead...
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A cluster of conditions that frequently co-occur, can be local or widespread, and either solely or predominantly affect women are referred to as chronic overlapping pain conditions. They include:
- Endometriosis
- Fibromyalgia
- Painful bladder syndrome
- Irritable bowel syndrome
- Chronic low back...
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Delta opioid receptors have a built-in mechanism for pain relief and can be precisely targeted with drug-delivering nanoparticles--making them a promising target for treating chronic inflammatory pain with fewer side effects, according to a new study from an international team of researchers. The...
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Newswise — There is no cure for the more than 1.6 million people in the United States living with Crohn’s disease (CD) and its symptoms, including abdominal pain, intestinal distress and severe weight-loss. CD is a form of inflammatory bowel disease (IBD) in which the body’s own immune system...
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Newswise — Scientists at McMaster University have identified new biomarkers for Irritable Bowel Syndrome (IBS) in urine, which could lead to better treatments and reduce the need for costly and invasive colonoscopy procedures currently used for diagnosis.
Little is known about the causes of IBS...
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The U.S. Food and Drug Administration today permitted marketing of the first medical device to aid in the reduction of functional abdominal pain in patients 11-18 years of age with irritable bowel syndrome (IBS) when combined with other therapies for IBS. IBS is a condition affecting the large...
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Researchers from Washington University School of Medicine report that they have isolated a possible new target for the treatment of inflammatory bowel diseases (IBD) including Crohn’s disease and ulcerative colitis. Existing therapies for IBD focus on the patient’s overactive immune system and its...