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The lamprey is an eel-like creature in which researchers have found a protein called parapinopsin. This discovery was part of the research used to determine how brain neurons work, and may be controlled. The parapinopsin inhibited neurons, and turned off brain circuits. A similar system could be...
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Optimal treatment of rheumatoid arthritis involves more than evaluation of inflammation and disease progression. RA is one of the 50 most common diseases, affecting 1.3 million people in the US and 15 million worldwide. Evaluation and detection of RA should involve other factors that may influence...
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Along with the potential benefits of working from home, such as flexibility and the time- and cost-savings of not commuting, some people are experiencing increased back pain, wrist pain, and overuse pain. Although issues from sitting too long at a desk are not new, they are increasing along with the...
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Pain, chronic pain, anxiety, depression, opioids. A study presented at the Association of Academic Physiatrists Annual Meeting linked all of those to "the socially disadvantaged" and stated that more needs to be done to improve patient outcomes. A lack of access to nonpharmacological therapy, such...
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Osteoarthritis, the 5th-leading cause of disability in the US, may have met its match. Paroxetine is a selective serotonin reuptake inhibitor commonly used to treat depression and a potent inhibitor of the enzyme G protein-coupled receptor kinase 2 (GRK2). Patients with either osteoarthritis (OA) or...
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Medication and/or psychotherapy does not work for approximately 30% of patients with major depression. How can practitioners help those who are unresponsive? Brain stimulation may help, but for every person with a mental disorder, there may be a different manifestation and potential response to...
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A patient with multiple sclerosis experiences pain, tiredness, and a reduction in function. A co-occurring effect? Depression. An article in Annals of Behavioral Medicine looks at that depression and examines the benefit of earlier treatment. In an 8-week study, 154 adults with MS participated in an...
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Researchers reviewed 26 relevant studies of presurgical psychological predictors on the outcomes of knee or hip surgery and found that “there is evidential value for the effect of depression on pain intensity and function, anxiety on pain intensity and function, pain catastrophizing on pain...
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A study in the Journal of the American Geriatrics Society of 568 people surveyed found that 15% used cannabis within the past 3 years, over 50% of those surveyed used it regularly (daily or weekly), and 78% used it for self-medicating. Patients reported most commonly smoking, taking tinctures, or...
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According to a study in the Journal of the American Osteopathic Association, mindfulness helped improve the coping skills of those in chronic pain. It was a small study of 28 participants, 89% of whom had positive results from an 8-week group course in mindfulness-based stress reduction. Guided by...