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An international clinical trial published in the Lancet focuses on preserving muscle function in Duchenne muscular dystrophy, a rare but fatal genetic disorder. Caused by an absence of dystrophin, a protein that helps keep muscle cells intact, the disorder is characterized by progressive muscle...
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A new consensus report released last week by a panel of the National Academies of Sciences, Engineering, and Medicine urges a broad-based rethinking of our approach to chronic pain management, which would require changes in outlook and behavior from all stakeholders, including clinicians, patients...
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The Federation of State Medical Boards (FSMB) recently released an updated version of its guidelines for prescribers in the use of opioid therapy for chronic pain. The revised document draws on recent advisories from the CDC and the FDA, and is intended to reflect the most current science for...
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Dr. Fillingim discusses the evidence suggesting that changes in structure and function of the brain contribute to the pathophysiology of chronic pain. Drawing on a conceptual model of pain as on a continuum of peripheral and central contributors, the tailoring of brain vs body-focused treatment...
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New research from the University of California, San Francisco appears to link chronic pain in older adults to accelerated cognitive decline and dementia. In the longitudinal population based cohort study, a finding of pain in 2 interviews conducted 2 years apart was associated with a statistically...
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Results of a study published last week in the Journal of Pain Research provided confirming evidence that many providers lack confidence in their capacity to manage patients with chronic pain. Conducted by researchers from the Mayo Clinic, the study surveyed 83 attendees at a Mayo Clinic medical...
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There’s new information and further confirmation of the benefits of breastfeeding, according to research findings from colleagues at the Hospital Universitario Nuestra Senora de Valme in Spain. In their presentation at the Euroanaesthesia Congress 2017 in Geneva, the team reports that new mothers...
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Another milestone in the search for a new and better molecule for pain management may have been achieved by findings from new research led by Columbia University Medical Center (CUMC). Based on their experiments on rodents, the study team concludes that chronic pain may result from the migration of...
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New research on mouse models may provide a greater understanding of the connection between pain intensity and sleep loss, a topic that has been explored in the past by various members of the PAINWeek faculty. Sleep psychologist Chloe Alexandre, PhD, and pain psychologist Alban Latremoliere, PhD, led...
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A research team led by Eóin McNamee, PhD, at University of Colorado-Anschutz Medical Campus, has identified a microRNA produced by white blood cells that can modulate the inflammasome responsible for inflammatory bowel diseases (IBD), including Crohn’s disease and ulcerative colitis. The study in...