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As healthcare providers, we often encounter challenges in managing diabetic peripheral neuropathy (DPN) and chemotherapy-induced peripheral neuropathy (CIPN). At PAINWeek, we believe that education is the best analgesic. Today, we highlight key considerations and recent developments in the treatment...
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Jacques Cousteau said, “We forget that the water cycle and the life cycle are one." Water enriched with hydrogen molecules, which has had positive results when used as treatment in Alzheimer’s disease as well as depression, is now being studied for potential treatment of neurologic pain and its...
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Neuropathic pain affects between 3% and 17% of the population. The journal Cureus offers a narrative review of neuropathic pain, stating that early and accurate diagnosis is paramount in improving pain control and outcomes. In this review, researchers provide updated information on neurological...
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Exercise Rehabilitation in Veteran Cancer Survivors is a clinical trial from the Baltimore VA Medical Center. It seeks to determine the efficacy of exercise for patients who have survived lung cancer but have neuropathic pain, a common problem after surgery and chemotherapy. “The ultimate goal of...
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An article published in the Journal of Experimental Medicine connects the dots between neuropathic pain caused by chemotherapy and normalization of cholesterol. The article states that “Neuroinflammation is a major component in the transition to and perpetuation of neuropathic pain states.” If...
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A narrative review of minocycline—a 2nd-generation, semi-synthetic tetracycline used as a broad-spectrum antibiotic with anti-inflammatory properties—was performed by researchers evaluating its effectiveness in lessening neuropathic pain. Results were published in the Journal of Pain Research. A...
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Chemotherapy-induced neuropathic pain (CINP) is seen in up to 70% of cancer patients. Unfortunately, there is no effective treatment, and CINP causes many people to terminate their chemotherapy treatments. In a study published in the Journal of Pain Research, mice were separated into 4 test groups...
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In an article in the PNAS journal, researchers report the power of 3 antibiotics against chronic pain, possibly reducing the need for opioids. The study abstract reports that “demeclocycline, chlortetracycline, and minocycline can be repurposed for treatment of neuropathic pain and potentially for...
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Neuropathic pain—from an injury or disease of the peripheral and/or somatosensory nervous system—is usually severe and chronic, resistant to treatment, and therefore challenging for clinicians attempting to help patients. Researchers noted the high impact of neuropathic pain: "Many people with...